I tend to use the same programs on an almost daily basis. Many times I wish that one software product had a small feature that is available in another. For example, both Corel Draw and Microsoft Word have a "repeat the last thing I just did" shortcut key. (The shortcut is Ctrl+R in Corel and Ctrl+Y in Word.) I basically wish EVERY program had that feature. Realistically, if you do something once, you might want to do it again.
Along the same lines, Macromedia (now Adobe) Dreamweaver has two menu items I use all the time. Save All and Close All. Because I have a lot of HTML files open at once, they are extremely handy commands, especially at the end of the day when I want to save, bail out of everything. and step away from the computer.
Word is another program I almost always have open. In my case, I'm a rebel and still run Word 2000. It's always sort of annoyed me that there's no Save All or Close All options, since I often have quite a number of Word files open at a given time. As an aside, here's another keyboard shortcut, use Ctrl+F6 to switch among your open documents.
Yes, I could customize the menus, but I never bothered. But as it turns out Word has a hidden way to access the Save All and Close All menu options. If you hold down the Shift key while you click the File menu, there they are! If you use other Office programs, try this trick in those applications too.